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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1774236
Molecular formula	C21H22F4N4O
IUPAC name	2-[[(3S,4S)-4-[2-fluoro-4-(trifluoromethoxy)phenyl]-3-methylpiperidin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridine
Molecular weight	422.428
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50343328 cis-2-(((3S,4S)-4-(2-fluoro-4-(trifluoromethoxy)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine
Inchi Key	CQTZXNPIJZSXKK-HIFRSBDPSA-N
Inchi ID	InChI=1S/C21H22F4N4O/c1-13-11-29(12-19-27-20-18(28(19)2)4-3-8-26-20)9-7-15(13)16-6-5-14(10-17(16)22)30-21(23,24)25/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m1/s1
PubChem CID	51354020
ChEMBL	CHEMBL1774236
IUPHAR	N/A
BindingDB	50343328
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
48405	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558760	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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