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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Rfamide
Molecular formula	C15H24N6O2
IUPAC name	(2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight	320.397
Hydrogen bond acceptor	4
Hydrogen bond donor	5
XlogP	-2.0
Synonyms	Arg-phe-NH2 (S)-2-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide CHEMBL3343990 AC1L3U57 n5-(diaminomethylidene)-l-ornithyl-l-phenylalaninamide arginylphenylalaninamide SCHEMBL1373212 119051-99-9 H-Arg-Phe-NH2 AC1Q5IPT R-F-NH2 (2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide ZINC2554967 34388-59-5 L-Phenylalaninamide, L-arginyl- [ Show all ]
Inchi Key	CQZWLVDDIOZTJI-RYUDHWBXSA-N
Inchi ID	InChI=1S/C15H24N6O2/c16-11(7-4-8-20-15(18)19)14(23)21-12(13(17)22)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H2,17,22)(H,21,23)(H4,18,19,20)/t11-,12-/m0/s1
PubChem CID	122185
ChEMBL	CHEMBL3343990
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443620	Mas-related G-protein coupled receptor member X1	Q8CIP3	Mrgprx1	Mus musculus (Mouse)	322
443621	Mas-related G-protein coupled receptor member X1	Q8R4G1	Mrgprx1	Rattus norvegicus (Rat)	323
443622	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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