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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1992715
Molecular formula	C20H18ClN3O
IUPAC name	1-chloro-N-(4-pyrrolidin-3-ylphenyl)isoquinoline-3-carboxamide
Molecular weight	351.834
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.0
Synonyms	CHEMBL3953959 1312567-62-6 BDBM250198 US9452980, 108 3-Isoquinolinecarboxamide, 1-chloro-N-[4-(3-pyrrolidinyl)phenyl]-
Inchi Key	CRXUAVINIRWJJJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18ClN3O/c21-19-17-4-2-1-3-14(17)11-18(24-19)20(25)23-16-7-5-13(6-8-16)15-9-10-22-12-15/h1-8,11,15,22H,9-10,12H2,(H,23,25)
PubChem CID	53251264
ChEMBL	CHEMBL3953959
IUPHAR	N/A
BindingDB	250198
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537224	Trace amine-associated receptor 1	Q923Y9	Taar1	Rattus norvegicus (Rat)	332
537225	Trace amine-associated receptor 1	Q923Y8	Taar1	Mus musculus (Mouse)	332

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