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Ligand

NameCIPRALISANT
Molecular formulaC14H20N2
IUPAC name5-[(1R,2R)-2-(5,5-dimethylhex-1-ynyl)cyclopropyl]-1H-imidazole
Molecular weight216.328
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP3.3
SynonymsLS-191791
5-[(1R,2R)-2-(5,5-dimethylhex-1-ynyl)cyclopropyl]-1H-imidazole
ZINC3823435
213027-19-1
AC1O52EX
[ Show all ]
Inchi KeyCVKJAXCQPFOAIN-VXGBXAGGSA-N
Inchi IDInChI=1S/C14H20N2/c1-14(2,3)7-5-4-6-11-8-12(11)13-9-15-10-16-13/h9-12H,5,7-8H2,1-3H3,(H,15,16)/t11-,12-/m1/s1
PubChem CID6450823
ChEMBLCHEMBL278462
IUPHAR1244
BindingDB50074629, 50222968
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
51537Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
51536Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
51532Histamine H3 receptorQ9Y5N1HRH3Homo sapiens (Human)445
51533Histamine H3 receptorQ9QYN8Hrh3Rattus norvegicus (Rat)445
51535Histamine H3 receptorP58406Hrh3Mus musculus (Mouse)445
555669Histamine H3 receptorQ9JI35HRH3Cavia porcellus (Guinea pig)445
51534Histamine H4 receptorQ9H3N8HRH4Homo sapiens (Human)390

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