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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CIPRALISANT
Molecular formula	C14H20N2
IUPAC name	5-[(1R,2R)-2-(5,5-dimethylhex-1-ynyl)cyclopropyl]-1H-imidazole
Molecular weight	216.328
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.3
Synonyms	4-[(1R,2R)-2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl]-1H-imidazole GTPL1244 Cipralisant [INN] SCHEMBL7069804 (1R,2R)-4-(2-(5,5-Dimethylhex-1-ynyl)cyclopropyl)imidazole 309713XSKW BDBM50074629 D0Q5YF 4-[(1R,2R)-2-(5,5-dimethylhex-1-ynyl)cyclopropyl]-3H-imidazole CHEMBL278462 HY-106993 CS-0027076 UNII-309713XSKW 4-((1R,2R)-2-(5,5-Dimethylhex-1-ynyl)cyclopropyl)-1H-imidazole BDBM50222968 GT-2331 5-[(1R,2R)-2-(5,5-dimethylhex-1-ynyl)cyclopropyl]-1H-imidazole LS-191791 AC1O52EX CVKJAXCQPFOAIN-VXGBXAGGSA-N ZINC3823435 213027-19-1 [ Show all ]
Inchi Key	CVKJAXCQPFOAIN-VXGBXAGGSA-N
Inchi ID	InChI=1S/C14H20N2/c1-14(2,3)7-5-4-6-11-8-12(11)13-9-15-10-16-13/h9-12H,5,7-8H2,1-3H3,(H,15,16)/t11-,12-/m1/s1
PubChem CID	6450823
ChEMBL	CHEMBL278462
IUPHAR	1244
BindingDB	50074629, 50222968
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51537	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
51536	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
51532	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
51533	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
51535	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445
555669	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
51534	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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