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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AMD 3465
Molecular formula	C24H38N6
IUPAC name	N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine
Molecular weight	410.61
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	0.8
Synonyms	N-[1,4,8,11-Tetraazacyclotetradecanyl-1,4-phenylenebis(methylene)]-2-(amino-methyl)pyridine 185991-07-5 AMD 3465 (Hexahydrobromide) CHEMBL477121 HY-15971A UNII-IMD9Z48ZTT AMD3465 N-(2-pyridylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine AKOS030526677 BDBM50270276 Pyridin-2-ylmethyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmethyl)-benzyl]-amine 185991-24-6 AMD-3465 CS-2786 IMD9Z48ZTT ZINC19361903 AC1LA8MA AMD3465 (Hexahydrobromide) N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine 1-(pyridin-2-yl)-n-[4-(1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)benzyl]methanamine SCHEMBL13527941 2-Pyridinemethanamine, N-((4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl)methyl)- AMD-3465 (Hexahydrobromide) FT-0689764 MolPort-044-561-123 AC1Q4X3R AMD3465 hexahydrobromide [ Show all ]
Inchi Key	CWJJHESJXJQCJA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2
PubChem CID	483559
ChEMBL	CHEMBL477121
IUPHAR	N/A
BindingDB	50270276
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52140	C-X-C chemokine receptor type 4	P61073	CXCR4	Homo sapiens (Human)	352

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