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Ligand

NameCHEMBL1688377
Molecular formulaC18H25N3OS
IUPAC name1-adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanone
Molecular weight331.478
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP3.3
SynonymsAKOS027621387
BDBM50339075
Inchi KeyCXTMBWBHTXAOFX-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H25N3OS/c22-16(18-10-13-7-14(11-18)9-15(8-13)12-18)20-2-4-21(5-3-20)17-19-1-6-23-17/h1,6,13-15H,2-5,7-12H2
PubChem CID18138918
ChEMBLCHEMBL1688377
IUPHARN/A
BindingDB50339075
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
53131Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
53135Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
53136Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
53134Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
53133Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
53137Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
53132Metabotropic glutamate receptor 7Q14831GRM7Homo sapiens (Human)915
53138Metabotropic glutamate receptor 8O00222GRM8Homo sapiens (Human)908

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