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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3818669
Molecular formula	C20H20N2O2
IUPAC name	2-[4-(1,3-dihydroisoindol-2-yl)butyl]isoindole-1,3-dione
Molecular weight	320.392
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.3
Synonyms	SCHEMBL20358477 BDBM50182744
Inchi Key	CXXWGJNYYONTKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2O2/c23-19-17-9-3-4-10-18(17)20(24)22(19)12-6-5-11-21-13-15-7-1-2-8-16(15)14-21/h1-4,7-10H,5-6,11-14H2
PubChem CID	127052466
ChEMBL	CHEMBL3818669
IUPHAR	N/A
BindingDB	50182744
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
523084	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
523086	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
523082	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
523079	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
523087	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
523083	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
523085	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
523081	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
523080	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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