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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3421893
Molecular formula	C28H27Cl2N3O4
IUPAC name	ethyl 3-[2,5-dichloro-4-[3-(4-cyclopropyl-2,3-dihydroquinoxaline-1-carbonyl)pyridin-4-yl]oxyphenyl]propanoate
Molecular weight	540.441
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.6
Synonyms	BDBM50081124
Inchi Key	DCANVTYBPWSTEA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H27Cl2N3O4/c1-2-36-27(34)10-7-18-15-22(30)26(16-21(18)29)37-25-11-12-31-17-20(25)28(35)33-14-13-32(19-8-9-19)23-5-3-4-6-24(23)33/h3-6,11-12,15-17,19H,2,7-10,13-14H2,1H3
PubChem CID	71626765
ChEMBL	CHEMBL3421893
IUPHAR	N/A
BindingDB	50081124
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443924	G-protein coupled bile acid receptor 1	Q8TDU6	GPBAR1	Homo sapiens (Human)	330
443925	G-protein coupled bile acid receptor 1	Q80SS6	Gpbar1	Mus musculus (Mouse)	329

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