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Ligand

NameAripiprazole lauroxil
Molecular formulaC36H51Cl2N3O4
IUPAC name[7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate
Molecular weight660.721
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP10.0
SynonymsCHEBI:90930
RDC-3317
1259305-29-7
Aristada
ZINC95564895
[ Show all ]
Inchi KeyDDINXHAORAAYAD-UHFFFAOYSA-N
Inchi IDInChI=1S/C36H51Cl2N3O4/c1-2-3-4-5-6-7-8-9-10-16-35(43)45-28-41-33-27-30(19-17-29(33)18-20-34(41)42)44-26-12-11-21-39-22-24-40(25-23-39)32-15-13-14-31(37)36(32)38/h13-15,17,19,27H,2-12,16,18,20-26,28H2,1H3
PubChem CID49831411
ChEMBLN/A
IUPHARN/A
BindingDBN/A
DrugBankDB14185

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 24
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
5485405-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5485555-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
5485375-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
5485385-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
5485595-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5485525-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
5485395-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
5485545-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
548542Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
548551Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
548549Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
548545Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
548546Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
548543D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
548541D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
548558D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
548548D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
548557D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
548556Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
548547Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460

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