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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL2344437
Molecular formula	C35H40N6O2
IUPAC name	N-[[(3R,5R)-3-[3-(diaminomethylideneamino)propyl]-1-(2,2-diphenylethyl)-2-oxo-1,4-diazepan-5-yl]methyl]naphthalene-2-carboxamide
Molecular weight	576.745
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	4.4
Synonyms	CHEMBL3975851 BDBM230656 US9340517, 105
Inchi Key	DKFQXTHTGAKMJQ-XLJNKUFUSA-N
Inchi ID	InChI=1S/C35H40N6O2/c36-35(37)38-20-9-16-32-34(43)41(24-31(26-11-3-1-4-12-26)27-13-5-2-6-14-27)21-19-30(40-32)23-39-33(42)29-18-17-25-10-7-8-15-28(25)22-29/h1-8,10-15,17-18,22,30-32,40H,9,16,19-21,23-24H2,(H,39,42)(H4,36,37,38)/t30-,32-/m1/s1
PubChem CID	57854192
ChEMBL	CHEMBL3975851
IUPHAR	N/A
BindingDB	230656
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
534196	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
534194	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
534192	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
534193	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
534195	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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