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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1631865
Molecular formula	C27H24F3N3O
IUPAC name	4-[3-(2-cyclopentylpyridin-4-yl)phenyl]-7-methyl-8-(trifluoromethyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	463.504
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.9
Synonyms	DKJNQISCRXNASW-UHFFFAOYSA-N 4-[3-(2-Cyclopentyl-pyridin-4-yl)-phenyl]-7-methyl-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one SCHEMBL5565155 4-(3-(2-cyclopentylpyridin-4-yl)phenyl)-7-methyl-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one BDBM50332984
Inchi Key	DKJNQISCRXNASW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H24F3N3O/c1-16-11-24-25(14-21(16)27(28,29)30)33-26(34)15-23(32-24)20-8-4-7-18(12-20)19-9-10-31-22(13-19)17-5-2-3-6-17/h4,7-14,17H,2-3,5-6,15H2,1H3,(H,33,34)
PubChem CID	22317279
ChEMBL	CHEMBL1631865
IUPHAR	N/A
BindingDB	50332984
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62351	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559194	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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