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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL168541
Molecular formula	C21H24N4O
IUPAC name	(4S)-2-phenyl-4-[(4-phenylpiperazin-1-yl)methyl]-4,5-dihydro-1H-pyrimidin-6-one
Molecular weight	348.45
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.3
Synonyms	(6S)-2-Phenyl-6beta-(4-phenylpiperazinomethyl)-3,4,5,6-tetrahydropyrimidine-4-one BDBM50124196 (S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Inchi Key	DKXYPAWNMBQJBN-SFHVURJKSA-N
Inchi ID	InChI=1S/C21H24N4O/c26-20-15-18(22-21(23-20)17-7-3-1-4-8-17)16-24-11-13-25(14-12-24)19-9-5-2-6-10-19/h1-10,18H,11-16H2,(H,22,23,26)/t18-/m0/s1
PubChem CID	44381276
ChEMBL	CHEMBL168541
IUPHAR	N/A
BindingDB	50124196
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62704	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
62707	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
62705	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
62706	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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