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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL539516
Molecular formula	C21H20N2O4
IUPAC name	(2R,4R)-4-amino-1-[[2-(2-phenylethynyl)phenyl]methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight	364.401
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-2.5
Synonyms	(2R,4R)-4-Amino-1-(2-phenylethynyl-benzyl)-pyrrolidine-24-dicarboxylic acid; dihydrochloride CHEMBL1189797 (2R)-1-[2-(Phenylethynyl)benzyl]-4-aminopyrrolidine-2beta,4alpha-dicarboxylic acid BDBM50102127
Inchi Key	DLMCYSYJJKBPGP-WIYYLYMNSA-N
Inchi ID	InChI=1S/C21H20N2O4/c22-21(20(26)27)12-18(19(24)25)23(14-21)13-17-9-5-4-8-16(17)11-10-15-6-2-1-3-7-15/h1-9,18H,12-14,22H2,(H,24,25)(H,26,27)/t18-,21-/m1/s1
PubChem CID	10250423
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50102127
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459792	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
63097	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

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