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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL87370
Molecular formula	C20H16F3N3O
IUPAC name	(E)-N-(4-amino-2-methylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight	371.363
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.1
Synonyms	SCHEMBL6204654 (E)-N-(4-Amino-2-methyl-6-quinolinyl)-4-trifluoromethylcinnamamide SCHEMBL6204655 BDBM50193649 N-(4-Amino-2-methyl-quinolin-6-yl)-3-(4-trifluoromethyl-phenyl)-acrylamide (E)-N-(4-amino-2-methylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide [ Show all ]
Inchi Key	DOZGFBDFGIPWCL-RUDMXATFSA-N
Inchi ID	InChI=1S/C20H16F3N3O/c1-12-10-17(24)16-11-15(7-8-18(16)25-12)26-19(27)9-4-13-2-5-14(6-3-13)20(21,22)23/h2-11H,1H3,(H2,24,25)(H,26,27)/b9-4+
PubChem CID	15133403
ChEMBL	CHEMBL87370
IUPHAR	N/A
BindingDB	50193649
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65474	C5a anaphylatoxin chemotactic receptor 1	P21730	C5AR1	Homo sapiens (Human)	350
65473	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
65472	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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