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Ligand

NameCHEMBL87370
Molecular formulaC20H16F3N3O
IUPAC name(E)-N-(4-amino-2-methylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight371.363
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP4.1
Synonyms(E)-N-(4-Amino-2-methyl-6-quinolinyl)-4-trifluoromethylcinnamamide
SCHEMBL6204655
BDBM50193649
N-(4-Amino-2-methyl-quinolin-6-yl)-3-(4-trifluoromethyl-phenyl)-acrylamide
(E)-N-(4-amino-2-methylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
[ Show all ]
Inchi KeyDOZGFBDFGIPWCL-RUDMXATFSA-N
Inchi IDInChI=1S/C20H16F3N3O/c1-12-10-17(24)16-11-15(7-8-18(16)25-12)26-19(27)9-4-13-2-5-14(6-3-13)20(21,22)23/h2-11H,1H3,(H2,24,25)(H,26,27)/b9-4+
PubChem CID15133403
ChEMBLCHEMBL87370
IUPHARN/A
BindingDB50193649
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
65474C5a anaphylatoxin chemotactic receptor 1P21730C5AR1Homo sapiens (Human)350
65473Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
65472Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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