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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000035540
Molecular formula	C12H14N2OS2
IUPAC name	2-ethylsulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
Molecular weight	266.377
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.2
Synonyms	AKOS000281442 2-(ethylthio)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one SMR000123047 2-ethylthio-3,5,6,7,8-pentahydrobenzo[b]thiopheno[2,3-d]pyrimidin-4-one HMS2418G12 ZINC8716811 2-(ethylsulfanyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one BAS 01258242 MolPort-000-565-235 2-Ethylsulfanyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one CHEMBL567861 ST096726 AC1LGASW MCULE-4383942554 2-(ethylthio)-5,6,7,8-tetrahydro-3H-benzothiopheno[2,3-d]pyrimidin-4-one BDBM50858 MolPort-000-850-888 2-ethylsulfanyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one cid_767975 STK830537 [ Show all ]
Inchi Key	DPLLLUXBJYFAKR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H14N2OS2/c1-2-16-12-13-10(15)9-7-5-3-4-6-8(7)17-11(9)14-12/h2-6H2,1H3,(H,13,14,15)
PubChem CID	767975
ChEMBL	CHEMBL567861
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65726	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
65727	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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