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Ligand

NameDoproston
Molecular formulaC20H34O4
IUPAC name7-[(1R,2R)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight338.488
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP4.2
Synonyms11-deoxy-Prostaglandin E1
AKOS032429044
HMS3648B09
SR-01000946400-1
D0G5MT
[ Show all ]
Inchi KeyDPNOTBLPQOITGU-LDDQNKHRSA-N
Inchi IDInChI=1S/C20H34O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,16-18,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1
PubChem CID5283055
ChEMBLN/A
IUPHAR1925
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
553581Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
553584Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
553579Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
553582Prostaglandin E2 receptor EP3 subtypeP34980Ptger3Rattus norvegicus (Rat)365
553580Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488
553583Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513

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