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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UPIDOSIN
Molecular formula	C31H33N3O4
IUPAC name	N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-methyl-4-oxo-2-phenylchromene-8-carboxamide
Molecular weight	511.622
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.8
Synonyms	N-(3-(4-(o-Methoxyphenyl)-1-piperazinyl)propyl)-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxamide SB-216469 UNII-TXG28R7G4Y D09TDS Rec 15/2739 ZINC3796141 152735-23-4 AKOS030553705 GTPL496 SB 216469 4H-1-Benzopyran-8-carboxamide, N-(3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)-3-methyl-4-oxo-2-phenyl- CHEMBL278865 N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-methyl-4-oxo-2-phenylchromene-8-carboxamide SCHEMBL6638869 AC1L3XX2 D0P9FT Rec-15-2739 3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide BDBM50057465 L000508 SB 216469-S TXG28R7G4Y 4H-1-Benzopyran-8-carboxamide,N-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]-3-methyl-4-oxo-2-phenyl- CTK4C7558 Rec 15-2739 Upidosin [INN] ACMC-20n6iu DTXSID70165115 REC-22/009 [ Show all ]
Inchi Key	DUCNHKDCVVSJLG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H33N3O4/c1-22-28(35)24-12-8-13-25(30(24)38-29(22)23-10-4-3-5-11-23)31(36)32-16-9-17-33-18-20-34(21-19-33)26-14-6-7-15-27(26)37-2/h3-8,10-15H,9,16-21H2,1-2H3,(H,32,36)
PubChem CID	148842
ChEMBL	CHEMBL278865
IUPHAR	496
BindingDB	50057465
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68892	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
68888	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
68889	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
68890	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
68891	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
68887	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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