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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	3-hydroxy-1-(6-methylpyridin-2-yl)-5-[4-(propan-2-yl)phenyl]-4-(thiophen-2-ylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one
Molecular formula	C24H22N2O3S
IUPAC name	4-hydroxy-1-(6-methylpyridin-2-yl)-2-(4-propan-2-ylphenyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
Molecular weight	418.511
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.4
Synonyms	STK983037 (E)-{1-(6-methylpyridinium-2-yl)-4,5-dioxo-2-[4-(propan-2-yl)phenyl]pyrrolidin-3-ylidene}(thiophen-2-yl)methanolate MCULE-4467452188 384359-74-4 Oprea1_514710 AKOS005748410 CHEMBL1576217 STL148443 3-hydroxy-1-(6-methyl(2-pyridyl))-5-[4-(methylethyl)phenyl]-4-(2-thienylcarbon yl)-3-pyrrolin-2-one MolPort-000-433-281 AC1MXUNX ST50048157 AKOS016294850 HMS2798D08 MolPort-000-700-128 AKOS002169209 [ Show all ]
Inchi Key	DUJWEXPTWKQUEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22N2O3S/c1-14(2)16-9-11-17(12-10-16)21-20(22(27)18-7-5-13-30-18)23(28)24(29)26(21)19-8-4-6-15(3)25-19/h4-14,21,28H,1-3H3
PubChem CID	3771682
ChEMBL	CHEMBL1576217
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69126	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
69124	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
69125	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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