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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17334431
Molecular formula	C19H15ClF3N5O2
IUPAC name	5-(4-chloropyridin-2-yl)-2-[[4-(difluoromethoxy)-2-fluoroanilino]methyl]-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	437.807
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.7
Synonyms	5-(4-chloropyridin-2-yl)-2-(((4-(difluoromethoxy)-2-fluorophenyl)amino)methyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one US9676782, 139 BDBM197946
Inchi Key	DURFDXKRZZDSPR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H15ClF3N5O2/c20-11-3-4-24-17(7-11)27-5-6-28-16(18(27)29)8-12(26-28)10-25-15-2-1-13(9-14(15)21)30-19(22)23/h1-4,7-9,19,25H,5-6,10H2
PubChem CID	118575191
ChEMBL	N/A
IUPHAR	N/A
BindingDB	197946
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559472	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
559471	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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