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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Org41841
Molecular formula	C19H22N4O2S2
IUPAC name	5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
Molecular weight	402.531
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.5
Synonyms	301847-37-0 CS-0018422 Org 41841 BDBM50189778 HMS3355K22 SCHEMBL4326072 CHEMBL211405 N-tert-butyl-5-amino-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide Thieno(2,3-d)pyrimidine-6-carboxamide, 5-amino-N-(1,1-dimethylethyl)-4-(3-methoxyphenyl)-2-(methylthio)- 5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide DVSFSADBOJYPGF-UHFFFAOYSA-N Org-41841 CHEBI:93615 HY-100271 SMR000486397 cid_9887381 NCGC00165246-01 HMS2213G07 MLS001065923 tert-Butyl 5-amino-2-methylthio-4-(3-methoxyphenyl)-thieno[2,3-d]pyrimidine-6-carboxamide [ Show all ]
Inchi Key	DVSFSADBOJYPGF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N4O2S2/c1-19(2,3)23-16(24)15-13(20)12-14(10-7-6-8-11(9-10)25-4)21-18(26-5)22-17(12)27-15/h6-9H,20H2,1-5H3,(H,23,24)
PubChem CID	9887381
ChEMBL	CHEMBL211405
IUPHAR	N/A
BindingDB	50189778
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70180	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
70181	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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