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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL31714
Molecular formula	C29H21FN4OS
IUPAC name	5-fluoro-2-[(E)-2-[3-[[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]-1,3-benzothiazole
Molecular weight	492.572
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.8
Synonyms	SCHEMBL9334977 BDBM50284690 CP-96021 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]-benzyloxy}-phenyl)-2-methyl-1H-imidazo[4,5-c]pyridine SCHEMBL9527363 L005985 [ Show all ]
Inchi Key	DXTYGLAQRALLEG-LFYBBSHMSA-N
Inchi ID	InChI=1S/C29H21FN4OS/c1-19-32-26-17-31-14-13-27(26)34(19)23-7-9-24(10-8-23)35-18-21-4-2-3-20(15-21)5-12-29-33-25-16-22(30)6-11-28(25)36-29/h2-17H,18H2,1H3/b12-5+
PubChem CID	9848518
ChEMBL	CHEMBL31714
IUPHAR	N/A
BindingDB	50284690
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
71647	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
71649	Cysteinyl leukotriene receptor 1	Q2NNR5	CYSLTR1	Cavia porcellus (Guinea pig)	340
71650	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
71648	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
71651	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
71646	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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