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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3717221
Molecular formula	C25H23F5N6O2
IUPAC name	2-(cyclopropylamino)-3-[4-[(2,5-difluorophenyl)methyl]piperazin-1-yl]quinoxaline-6-carbonitrile;2,2,2-trifluoroacetic acid
Molecular weight	534.491
Hydrogen bond acceptor	13
Hydrogen bond donor	2
XlogP	None
Synonyms	N/A
Inchi Key	DYFSMZWCIRAOCV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22F2N6.C2HF3O2/c24-17-2-5-19(25)16(12-17)14-30-7-9-31(10-8-30)23-22(27-18-3-4-18)28-20-6-1-15(13-26)11-21(20)29-23;3-2(4,5)1(6)7/h1-2,5-6,11-12,18H,3-4,7-10,14H2,(H,27,28);(H,6,7)
PubChem CID	127024688
ChEMBL	CHEMBL3717221
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
523645	G-protein coupled receptor 6	P46095	GPR6	Homo sapiens (Human)	362

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