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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000536105
Molecular formula	C17H11ClF3N3O3S2
IUPAC name	(5Z)-3-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
Molecular weight	461.858
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	5.2
Synonyms	BDBM72022 cid_2321190 (5Z)-3-[[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]amino]-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (5Z)-3-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one MLS002637452 HMS2387P16 (5Z)-3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylidene-4-thiazolidinone AC1M53MS SMR000155363 CHEMBL1416493 (5Z)-3-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]amino]-2-thioxo-5-vanillylidene-thiazolidin-4-one [ Show all ]
Inchi Key	DYMWDFDNPDHJPE-ACAGNQJTSA-N
Inchi ID	InChI=1S/C17H11ClF3N3O3S2/c1-27-12-4-8(2-3-11(12)25)5-13-15(26)24(16(28)29-13)23-14-10(18)6-9(7-22-14)17(19,20)21/h2-7,25H,1H3,(H,22,23)/b13-5-
PubChem CID	2321190
ChEMBL	CHEMBL1416493
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72115	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
72116	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
72117	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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