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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1254742
Molecular formula	C27H33NO5
IUPAC name	N-[2-(2,6-diethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Molecular weight	451.563
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50416857
Inchi Key	DZWBHIPIKLFYOT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H33NO5/c1-3-29-25-15-10-16-26(30-4-2)27(25)32-20-18-28-17-19-31-23-13-8-9-14-24(23)33-21-22-11-6-5-7-12-22/h5-16,28H,3-4,17-21H2,1-2H3
PubChem CID	52945803
ChEMBL	CHEMBL1254742
IUPHAR	N/A
BindingDB	50416857
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
73090	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
73089	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
73092	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
73094	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
73095	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
73091	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
73093	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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