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Ligand

Name16-phenoxy tetranor Prostaglandin F2alpha
Molecular formulaC22H30O6
IUPAC name(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl]hept-5-enoic acid
Molecular weight390.476
Hydrogen bond acceptor6
Hydrogen bond donor4
XlogP2.1
Synonyms9.alpha.,11.alpha.,15R-Trihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
PGF2Alpha,16-Phenoxy
5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl)cyclopentyl)-, (5Z)-
SR-01000946502-1
1257AH
[ Show all ]
Inchi KeyFAPQZCFUFGJPFI-UEAHRUCRSA-N
Inchi IDInChI=1S/C22H30O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h1,3-6,8-9,12-13,16,18-21,23-25H,2,7,10-11,14-15H2,(H,26,27)/b6-1-,13-12+/t16-,18-,19-,20+,21-/m1/s1
PubChem CID5311234
ChEMBLCHEMBL334398
IUPHARN/A
BindingDB50106547
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
73628Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
73626Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
73629Prostaglandin F2-alpha receptorP37289PTGFRBos taurus (Bovine)362
73630Prostaglandin F2-alpha receptorP43088PTGFRHomo sapiens (Human)359
73627Thromboxane A2 receptorP21731TBXA2RHomo sapiens (Human)343

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