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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	851723-84-7
Molecular formula	C21H17FN2O2
IUPAC name	2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid
Molecular weight	348.377
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.4
Synonyms	DA-18057 KB-79648 OC-459 SB16523 Y0372 04XB9TB8OL 851723-84-7, 950688-14-9 (sodium salt) AM20120668 BDBM50296977 EX-A090 OC 000459 OC459 ST24039501 2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic Acid AB0035922 AX8237454 CHEMBL560993 CTK8C1481 HMS3651F15 OC-2125 S-7796 timapiprant AK-97093 BCP0726000084 DB11900 MolPort-023-219-145 OC-499 SC-93534 ZINC43120334 1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)- ANW-66760 C21H17FN2O2 CRTH2 antagonists (asthma/allergy), Oxagen FT-0729718 OC-000459 ODC-9101 SW219412-1 4CA-0934 ABP001054 BC600559 D0X7EG HY-15342 OC-2184 s2822 UNII-04XB9TB8OL (5-Fluoro-2-methyl-3-quinolin-2-ylmethylindo-1-yl)-acetic acid AKOS016007630 BCP9001018 DTXSID00234343 NCGC00386286-04 OC000459 SCHEMBL1782956 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid 950688-14-9 (sodium salt) AOB87167 CS-1285 GTPL9277 OC-1768 QC-10854 TC-155505 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-Indole-1-acetic acid AJ-108236 BCP04237 [ Show all ]
Inchi Key	FATGTHLOZSXOBC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26)
PubChem CID	11462174
ChEMBL	CHEMBL560993
IUPHAR	9277
BindingDB	50296977
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
73781	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
73782	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
73780	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
553639	Prostaglandin D2 receptor 2	Q6XKD3	Ptgdr2	Rattus norvegicus (Rat)	403
73783	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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