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Ligand

NameRivenprost
Molecular formulaC24H34O6S
IUPAC namemethyl 4-[2-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]butanoate
Molecular weight450.59
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP1.8
SynonymsAKOS027326542
methyl 4-[2-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxocyclopentyl]ethylsulfanyl]butanoate
4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3-methoxymethyl-phenyl)-but-1-enyl]-5-oxo-cyclopentyl}-ethylsulfanyl)-butyric acid methyl ester
CHEMBL303960
ONO-4819
[ Show all ]
Inchi KeyFBQUXLIJKPWCAO-AZIFJQEOSA-N
Inchi IDInChI=1S/C24H34O6S/c1-29-16-18-6-3-5-17(13-18)14-19(25)8-9-20-21(23(27)15-22(20)26)10-12-31-11-4-7-24(28)30-2/h3,5-6,8-9,13,19-22,25-26H,4,7,10-12,14-16H2,1-2H3/b9-8+/t19-,20-,21-,22-/m1/s1
PubChem CID9803828
ChEMBLCHEMBL303960
IUPHAR1930
BindingDB50318871
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
553641Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
74488Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
74489Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513

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