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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3318831
Molecular formula	C46H48Cl2F2N2O6
IUPAC name	bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] butanedioate
Molecular weight	833.795
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	8.4
Synonyms	BDBM50053376
Inchi Key	FCLHHKLNBKMBPS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C46H48Cl2F2N2O6/c47-37-13-9-35(10-14-37)45(23-29-51(30-24-45)27-1-3-41(53)33-5-17-39(49)18-6-33)57-43(55)21-22-44(56)58-46(36-11-15-38(48)16-12-36)25-31-52(32-26-46)28-2-4-42(54)34-7-19-40(50)20-8-34/h5-20H,1-4,21-32H2
PubChem CID	118709159
ChEMBL	CHEMBL3318831
IUPHAR	N/A
BindingDB	50053376
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
444668	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
444669	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
444667	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
444670	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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