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Ligand

Name8-Cyclopentyl-1,3-dipropylxanthine
Molecular formulaC16H24N4O2
IUPAC name8-cyclopentyl-1,3-dipropyl-7H-purine-2,6-dione
Molecular weight304.394
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP4.0
SynonymsKBio2_005887
LP00381
1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX]
NCGC00015177-04
8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
[ Show all ]
Inchi KeyFFBDFADSZUINTG-UHFFFAOYSA-N
Inchi IDInChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
PubChem CID1329
ChEMBLCHEMBL183
IUPHAR386
BindingDB21173
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 18
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
76819Adenosine receptor A1P28190ADORA1Bos taurus (Bovine)326
76820Adenosine receptor A1P25099Adora1Rattus norvegicus (Rat)326
76822Adenosine receptor A1P34970ADORA1Oryctolagus cuniculus (Rabbit)328
76823Adenosine receptor A1P30542ADORA1Homo sapiens (Human)326
76826Adenosine receptor A1P47745ADORA1Cavia porcellus (Guinea pig)326
76821Adenosine receptor A2aP29274ADORA2AHomo sapiens (Human)412
76825Adenosine receptor A2aP30543Adora2aRattus norvegicus (Rat)410
76827Adenosine receptor A2bP29276Adora2bRattus norvegicus (Rat)332
76828Adenosine receptor A2bP29275ADORA2BHomo sapiens (Human)332
553654Adenosine receptor A2bQ60614Adora2bMus musculus (Mouse)332
76824Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
76830Adenosine receptor A3P28647Adora3Rattus norvegicus (Rat)320
76834Adenosine receptor A3P35342ADORA3Ovis aries (Sheep)317
76835Adenosine receptor A3O02667ADORA3Oryctolagus cuniculus (Rabbit)319
76833Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
76836Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
76832P2Y purinoceptor 2P58825P2RY2Cricetulus griseus (Chinese hamster)166
76831Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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