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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-(2-chloropyridin-3-yl)-2-{6-[(diethylamino)sulfonyl]-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl}acetamide
Molecular formula	C19H21ClN4O5S
IUPAC name	N-(2-chloropyridin-3-yl)-2-[6-(diethylsulfamoyl)-3-oxo-1,4-benzoxazin-4-yl]acetamide
Molecular weight	452.91
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	1.7
Synonyms	MCULE-1267735111 CHEMBL1506287 MLS000674699 AKOS001833253 SMR000314140 HMS2685O08 MolPort-007-641-093 ZINC13521394 [ Show all ]
Inchi Key	FFYMMLDQZXKNSQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21ClN4O5S/c1-3-23(4-2)30(27,28)13-7-8-16-15(10-13)24(18(26)12-29-16)11-17(25)22-14-6-5-9-21-19(14)20/h5-10H,3-4,11-12H2,1-2H3,(H,22,25)
PubChem CID	16189472
ChEMBL	CHEMBL1506287
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77539	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
77538	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
77540	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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