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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000078105
Molecular formula	C16H12N4OS3
IUPAC name	3-amino-N-(4-methyl-1,3-thiazol-2-yl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide
Molecular weight	372.479
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.4
Synonyms	3-azanyl-N-(4-methyl-1,3-thiazol-2-yl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carboxamide cid_1596915 REGID_for_CID_1596915 AKOS003681095 MLS000064430 3-amino-N-(4-methyl-1,3-thiazol-2-yl)-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide 3-amino-N-(4-methylthiazol-2-yl)-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide Oprea1_293570 STK847432 371117-13-4 HMS2490A16 RSC000402 AKOS005627886 MolPort-000-762-006 SR-01000282976 3-amino-N-(4-methyl-1,3-thiazol-2-yl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide 3-amino-N-[(2E)-4-methyl-1,3-thiazol-2(3H)-ylidene]-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide CHEMBL1309478 regid4258465 ZINC17208330 AC1LV2Q8 MCULE-1367489980 SCHEMBL424863 BDBM76992 MolPort-000-921-496 SR-01000282976-1 3-amino-N-(4-methyl-2-thiazolyl)-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarboxamide [ Show all ]
Inchi Key	FMKRJNAUBWDCBD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H12N4OS3/c1-8-7-23-16(18-8)20-14(21)13-12(17)9-4-5-10(19-15(9)24-13)11-3-2-6-22-11/h2-7H,17H2,1H3,(H,18,20,21)
PubChem CID	1596915
ChEMBL	CHEMBL1309478
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
81985	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
81984	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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