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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3298273
Molecular formula	C15H13FN2O2
IUPAC name	2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-1,6-naphthyridin-5-one
Molecular weight	272.279
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.1
Synonyms	FMUAFDSEYCJYKD-UHFFFAOYSA-N 2-(3-Fluorobenzyloxy)-7,8-dihydro-1,6-naphthyridine-5(6H)-one SCHEMBL10009846 2-((3-fluorobenzyl)oxy)-7,8-dihydro-1,6-naphthyridin-5(6H)-one BDBM50022759
Inchi Key	FMUAFDSEYCJYKD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H13FN2O2/c16-11-3-1-2-10(8-11)9-20-14-5-4-12-13(18-14)6-7-17-15(12)19/h1-5,8H,6-7,9H2,(H,17,19)
PubChem CID	57405264
ChEMBL	CHEMBL3298273
IUPHAR	N/A
BindingDB	50022759
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
82274	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
82272	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559847	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
82270	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
82267	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
82268	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
82269	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
82273	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
82271	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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