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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3603923
Molecular formula	C16H8ClFN4
IUPAC name	3-chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile
Molecular weight	310.716
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.9
Synonyms	51E SCHEMBL16398553 3-Chloro-5-(6-(5-fluoro-2-pyridyl)-4-pyrimidinyl)benzonitrile 3-Chloro-5-[6-(5-Fluoropyridin-2-Yl)pyrimidin-4-Yl]benzonitrile HTL-14242 BDBM50113476 3-chloro-5-(6-(5-fluoropyridin-2-yl)pyrimidin-4-yl)benzonitrile CS-0054551 SB19195 1644645-32-8 3-Chloro-5-[6-(5-fluoro-2-pyridinyl)-4-pyrimidinyl]benzonitrile FQAXDSVNYVVQSE-UHFFFAOYSA-N [ Show all ]
Inchi Key	FQAXDSVNYVVQSE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H8ClFN4/c17-12-4-10(7-19)3-11(5-12)15-6-16(22-9-21-15)14-2-1-13(18)8-20-14/h1-6,8-9H
PubChem CID	86763358
ChEMBL	CHEMBL3603923
IUPHAR	N/A
BindingDB	50113476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
473332	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
473333	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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