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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL427860
Molecular formula	C30H43ClN4O2
IUPAC name	N-[(1S)-1-[2-[4-[(2R)-3-(4-chlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-5-methylphenyl]-2-methylpropyl]-3-(dimethylamino)propanamide
Molecular weight	527.15
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50224181 N-((S)-1-(2-(4-((R)-3-(4-chlorophenyl)-2-methylpropanoyl)piperazin-1-yl)-5-methylphenyl)-2-methylpropyl)-3-(dimethylamino)propanamide 1-{2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine SCHEMBL3727855
Inchi Key	FRHBHVROLQSPMW-BTYSJIOQSA-N
Inchi ID	InChI=1S/C30H43ClN4O2/c1-21(2)29(32-28(36)13-14-33(5)6)26-19-22(3)7-12-27(26)34-15-17-35(18-16-34)30(37)23(4)20-24-8-10-25(31)11-9-24/h7-12,19,21,23,29H,13-18,20H2,1-6H3,(H,32,36)/t23-,29+/m1/s1
PubChem CID	23635235
ChEMBL	CHEMBL427860
IUPHAR	N/A
BindingDB	50224181
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85420	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
85421	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
85416	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
85417	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
85419	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
85418	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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