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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1081902
Molecular formula	C23H14Cl2F3N3O3S2
IUPAC name	4,5-dichloro-N-[5-[1-[(3,4-difluorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-1,2-oxazol-3-yl]thiophene-2-sulfonamide
Molecular weight	572.398
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	6.8
Synonyms	BDBM50311613 SCHEMBL1924612 4,5-dichloro-N-(5-(1-(3,4-difluorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)isoxazol-3-yl)thiophene-2-sulfonamide
Inchi Key	FZNGBHCZAVIIKY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H14Cl2F3N3O3S2/c1-11-9-31(10-12-2-3-17(27)18(28)4-12)22-14(11)5-13(26)6-15(22)19-8-20(29-34-19)30-36(32,33)21-7-16(24)23(25)35-21/h2-9H,10H2,1H3,(H,29,30)
PubChem CID	46879756
ChEMBL	CHEMBL1081902
IUPHAR	N/A
BindingDB	50311613
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91070	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
91072	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
91068	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
91071	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
91069	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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