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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL424578
Molecular formula	C32H35Cl2N3O5
IUPAC name	1-[2-[(5R)-5-(3,4-dichlorophenyl)-3-(2,4-dimethoxybenzoyl)-1,3-oxazolidin-5-yl]ethyl]-4-phenylpiperidine-4-carboxamide
Molecular weight	612.548
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	1-[2-[(5R)-3-(2,4-Dimethoxybenzoyl)-5-(3,4-dichlorophenyl)-5alpha-oxazolidinyl]ethyl]-4-phenylpiperidine-4-carboxamide
Inchi Key	GECFPZABSKHOMR-YTTGMZPUSA-N
Inchi ID	InChI=1S/C32H35Cl2N3O5/c1-40-24-9-10-25(28(19-24)41-2)29(38)37-20-32(42-21-37,23-8-11-26(33)27(34)18-23)14-17-36-15-12-31(13-16-36,30(35)39)22-6-4-3-5-7-22/h3-11,18-19H,12-17,20-21H2,1-2H3,(H2,35,39)/t32-/m0/s1
PubChem CID	44382150
ChEMBL	CHEMBL424578
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
94203	Substance-K receptor	Q64077	TACR2	Cavia porcellus (Guinea pig)	402
94202	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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