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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1078208
Molecular formula	C23H28N4O3S
IUPAC name	4-propan-2-yloxy-N-[3-(1H-pyrazol-5-ylmethyl)-1,2,4,5-tetrahydro-3-benzazepin-7-yl]benzenesulfonamide
Molecular weight	440.562
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.4
Synonyms	BDBM50311416 N-(3-((1H-pyrazol-3-yl)methyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-4-isopropoxybenzenesulfonamide
Inchi Key	GHHKXCCOHHVPRP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N4O3S/c1-17(2)30-22-5-7-23(8-6-22)31(28,29)26-20-4-3-18-10-13-27(14-11-19(18)15-20)16-21-9-12-24-25-21/h3-9,12,15,17,26H,10-11,13-14,16H2,1-2H3,(H,24,25)
PubChem CID	46882522
ChEMBL	CHEMBL1078208
IUPHAR	N/A
BindingDB	50311416
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96499	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
96500	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
96498	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
96497	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
96501	Motilin receptor	O43193	MLNR	Homo sapiens (Human)	412

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