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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Skf-81297
Molecular formula	C16H16ClNO2
IUPAC name	9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight	289.759
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.7
Synonyms	6-Chloro-PB hydrobromide BRD-A09828896-004-04-5 CTK5D4764 NCGC00015910-03 SCHEMBL398776 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol CCG-205236 GHWJEDJMOVUXEC-UHFFFAOYSA-N NCGC00163159-01 SKF 81297 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol AC1Q3LHK CHEMBL353335 Lopac0_001162 PDSP2_001510 71636-61-8 C16H16ClNO2 D02DHU NCGC00015910-04 SK&F 81297 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl- 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol CHEBI:91517 GTPL938 NSC_1218 SKF 81297 hydrochloride 6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine BDBM86282 cid_11957706 LS-176906 R(+)SKF81297 SKF81297 CAS_1218 DTXSID3043815 NCGC00025166-02 SK&F-81297 1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl- 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide AC1L1AZH L000565 PDSP1_001526 SKF-81,297 [ Show all ]
Inchi Key	GHWJEDJMOVUXEC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2
PubChem CID	1218
ChEMBL	CHEMBL353335
IUPHAR	938
BindingDB	86282
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96856	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
555832	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
96862	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
96855	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
96857	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
96861	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555831	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
96860	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
96859	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
96858	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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