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Ligand

NameCHEMBL197280
Molecular formulaC27H26Cl2N4O
IUPAC name1-[[4-(3-cyanophenyl)phenyl]methyl]-3-(3,5-dichlorophenyl)-1-(2-pyrrolidin-1-ylethyl)urea
Molecular weight493.432
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP5.7
SynonymsBDBM50174822
1-(3''-cyano-biphenyl-4-ylmethyl)-3-(3,5-dichloro-phenyl)-1-(2-pyrrolidin-1-yl-ethyl)-urea
Inchi KeyGIOCKCZZIGNDMZ-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H26Cl2N4O/c28-24-15-25(29)17-26(16-24)31-27(34)33(13-12-32-10-1-2-11-32)19-20-6-8-22(9-7-20)23-5-3-4-21(14-23)18-30/h3-9,14-17H,1-2,10-13,19H2,(H,31,34)
PubChem CID44405437
ChEMBLCHEMBL197280
IUPHARN/A
BindingDB50174822
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
97396Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
97395Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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