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Ligand

NameCHEMBL194837
Molecular formulaC22H23Cl2N3O3
IUPAC name2-(2,4-dichlorophenoxy)-N-[2-[2-(dimethylamino)ethoxy]-4-methylquinolin-6-yl]acetamide
Molecular weight448.344
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP5.0
SynonymsBDBM50172414
SCHEMBL5910613
2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-ethoxy)-4-methyl-quinolin-6-yl]-acetamide
Inchi KeyGKDBTHSYQZTDAJ-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H23Cl2N3O3/c1-14-10-22(29-9-8-27(2)3)26-19-6-5-16(12-17(14)19)25-21(28)13-30-20-7-4-15(23)11-18(20)24/h4-7,10-12H,8-9,13H2,1-3H3,(H,25,28)
PubChem CID11539632
ChEMBLCHEMBL194837
IUPHARN/A
BindingDB50172414
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
985105-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
985095-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
985125-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
98514D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
98516D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
98515Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
98513Histamine H2 receptorP25021HRH2Homo sapiens (Human)359
98511Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
98507Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340
98508Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
98517Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466

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