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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	pimobendan
Molecular formula	C19H18N4O2
IUPAC name	3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Molecular weight	334.379
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.7
Synonyms	Pimobendan [USAN:INN] 3(2H)-Pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl- Pimobendanum [INN-Latin] ud cg 115 bs 9HTU209Z0N Vetmedin Acardi BCP0726000255 CTK5E4521 I06-2191 LS-129900 NCGC00274063-05 (+-)-UD-CG 115BS Pimobendan, >=98% (HPLC) 3(2H)-Pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-, (-)- s1550 6-(2-(4-Methoxyphenyl)-4,5-dihydro-1H-benzimidazol-5-yl)-5-methyl-3(2H)-pyridazinone UD-CG-115 AB01274800_02 AKOS015851937 CC-33793 dl-Pimobendan KS-1280 MCULE-4183495834 (+)-4,5-Dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-3(2H)-pyridazinone Pimobendan (Vetmedin) (-)-UD-CG 115BS 118428-38-9 Pimobendane [INN-French] 4,5-dihydro-6-[2-(4-methoxy-phenyl)-1h-benzimidazol-5-yl]-5-methyl-3 (2h)-pyridazinone SMR002530068 613JXV89SU UNII-613JXV89SU AC1L1J18 BC226374 CHEMBL24646 HMS3655I03 l-Pimobendan MolPort-016-633-233 (+-)-4,5-Dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-3(2H)-pyridazinone Pimobendan [INN-Spanish] Pimobendan, (+)- 3(2H)-Pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-, (+)- Racemic pinobendan 6-(2-(4-METHOXYPHENYL)-1H-BENZO[D]IMIDAZOL-5-YL)-5-METHYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE UD-CG 115 AB0008564 Z-8899 Acardi (TN) BDBM50282617 d-Pimobendan J-517984 LS-129901 (-)-4,5-Dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-3(2H)-pyridazinone Pimobendan, United States Pharmacopeia (USP) Reference Standard 3-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one SC-19312 6-[2-(4-Methoxy-phenyl)-1H-benzoimidazol-5-yl]-5-methyl-4,5-dihydro-2H-pyridazin-3-one UD-CG-115BS AB1011451 AKOS015967705 CHEBI:32003 DTXSID8048280 KSC-210-009 MLS006010188 (+)-Pimobendan Pimobendan - Vetmedin 118428-36-7 150P279 Pimobendanum 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone SW219717-1 74150-27-9 UNII-9HTU209Z0N AC1Q6OY4 BCP02958 CS-2143 HY-B0204 LS-129899 NCGC00274063-01 (+-)-4,5-Dihydro-6-(2-(p-methoxyphenyl)-5-benzimidazolyl)-5-methyl-3(2H)-pyridazinone Pimobendan [USAN:INN:BAN] Pimobendan, (-)- 3(2H)-Pyridazinone, 4,5-dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-, (+-)- RP18110 6-(2-(4-methoxyphenyl)-1H-benzo[d]imidazol-6-yl)-5-methyl-4,5-dihydropyridazin-3(2H)-one UD-CG 115 BS AB01274800-01 AK482253 BRN 4207330 D01133 KS-00000GXC LS-185069 Pimobendan (JAN/USAN/INN) (-)-Pimobendan 118428-37-8 pimobendane 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one SCHEMBL27623 6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one UDCG-115 AC-689 AN-1099 FT-0630830 KUC109647N MolPort-001-737-116 (+)-UD-CG 115BS Pimobendan for system suitability, European Pharmacopoeia (EP) Reference Standard [ Show all ]
Inchi Key	GLBJJMFZWDBELO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
PubChem CID	4823
ChEMBL	CHEMBL24646
IUPHAR	N/A
BindingDB	50282617
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99178	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
99179	Type-1 angiotensin II receptor	P25104	AGTR1	Bos taurus (Bovine)	359

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