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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001100829
Molecular formula	C25H26FN3O3
IUPAC name	1-[(3-fluoro-4-methoxyphenyl)methyl]-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide
Molecular weight	435.499
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.0
Synonyms	1-(3-fluoro-4-methoxy-benzyl)-N-(6-phenoxy-3-pyridyl)isonipecotamide CHEMBL1583610 1-[(3-fluoro-4-methoxyphenyl)methyl]-N-(6-phenoxy-3-pyridinyl)-4-piperidinecarboxamide MCULE-8463648328 BDBM97152 SR-01000828872 1-(3-fluoro-4-methoxybenzyl)-N-(6-phenoxy-3-pyridinyl)-4-piperidinecarboxamide cid_24819426 1-[(3-fluoro-4-methoxyphenyl)methyl]-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide SR-01000828872-2 1-[(3-fluoranyl-4-methoxy-phenyl)methyl]-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide HMS2990L09 SMR000669993 [ Show all ]
Inchi Key	GMHPZRMQPJRBMJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26FN3O3/c1-31-23-9-7-18(15-22(23)26)17-29-13-11-19(12-14-29)25(30)28-20-8-10-24(27-16-20)32-21-5-3-2-4-6-21/h2-10,15-16,19H,11-14,17H2,1H3,(H,28,30)
PubChem CID	24819426
ChEMBL	CHEMBL1583610
IUPHAR	N/A
BindingDB	97152
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99910	Galanin receptor type 3	O60755	GALR3	Homo sapiens (Human)	368
99909	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
475246	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
99911	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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