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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL123348
Molecular formula	C25H27N5O3
IUPAC name	ethyl (2Z)-2-[3-ethyl-3-methyl-5-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrrolidin-2-ylidene]acetate
Molecular weight	445.523
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.6
Synonyms	[3-Ethyl-3-methyl-5-oxo-1-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-pyrrolidin-(2Z)-ylidene]-acetic acid ethyl ester BDBM50281520
Inchi Key	GOVCKLDFCNZSSA-STZFKDTASA-N
Inchi ID	InChI=1S/C25H27N5O3/c1-4-25(3)15-22(31)30(21(25)14-23(32)33-5-2)16-17-10-12-18(13-11-17)19-8-6-7-9-20(19)24-26-28-29-27-24/h6-14H,4-5,15-16H2,1-3H3,(H,26,27,28,29)/b21-14-
PubChem CID	44348323
ChEMBL	CHEMBL123348
IUPHAR	N/A
BindingDB	50281520
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101589	Type-1 angiotensin II receptor	P25104	AGTR1	Bos taurus (Bovine)	359

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