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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL57634
Molecular formula	C25H32ClNO7Si
IUPAC name	5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2-(2-trimethylsilylethoxycarbonyl)-1,3-benzodioxole-2-carboxylic acid
Molecular weight	522.066
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	None
Synonyms	5-[(R)-2-[[(R)-beta-Hydroxy-3-chlorophenethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid 2-[2-(trimethylsilyl)ethyl] ester
Inchi Key	GOWLTXQHNMGHMA-NLDMFTSSSA-N
Inchi ID	InChI=1S/C25H32ClNO7Si/c1-16(27-15-20(28)18-6-5-7-19(26)14-18)12-17-8-9-21-22(13-17)34-25(33-21,23(29)30)24(31)32-10-11-35(2,3)4/h5-9,13-14,16,20,27-28H,10-12,15H2,1-4H3,(H,29,30)/t16-,20+,25?/m1/s1
PubChem CID	44300786
ChEMBL	CHEMBL57634
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101618	Beta-3 adrenergic receptor	P26255	Adrb3	Rattus norvegicus (Rat)	400

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