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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL499050
Molecular formula	C19H12Cl2FN5O2
IUPAC name	3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(6-chloro-1,8-naphthyridin-3-yl)propanamide
Molecular weight	432.236
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50272276 N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanamide
Inchi Key	GUXZMJXQQKUUOL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H12Cl2FN5O2/c20-11-5-10-6-13(9-24-18(10)23-8-11)25-16(28)3-4-17-26-19(27-29-17)14-2-1-12(22)7-15(14)21/h1-2,5-9H,3-4H2,(H,25,28)
PubChem CID	25034140
ChEMBL	CHEMBL499050
IUPHAR	N/A
BindingDB	50272276
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106030	Cannabinoid receptor 1	P20272	Cnr1	Rattus norvegicus (Rat)	473
106031	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
106028	Cannabinoid receptor 2	Q9QZN9	Cnr2	Rattus norvegicus (Rat)	360
106029	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360

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