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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL257178
Molecular formula	C20H15F4N3O3S
IUPAC name	4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-(trifluoromethylsulfonyl)butanamide
Molecular weight	453.412
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.2
Synonyms	BDBM50236303 4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(trifluoromethylsulfonyl)butanamide
Inchi Key	GVMNNUOOILCXIW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H15F4N3O3S/c21-14-7-5-13(6-8-14)19-15(16-10-12(11-25)4-9-17(16)26-19)2-1-3-18(28)27-31(29,30)20(22,23)24/h4-10,26H,1-3H2,(H,27,28)
PubChem CID	44447923
ChEMBL	CHEMBL257178
IUPHAR	N/A
BindingDB	50236303
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106373	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360
106374	C-X-C chemokine receptor type 2	P35344	CXCR2	Oryctolagus cuniculus (Rabbit)	358

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