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Ligand

NameCHEMBL289410
Molecular formulaC31H46ClN5O5
IUPAC name(2S)-2-[[(2R)-3-(2-chloro-1H-indol-3-yl)-2-[[2-[[(2S,6R)-2,6-dimethylpiperidine-1-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]hexanoic acid
Molecular weight604.189
Hydrogen bond acceptor5
Hydrogen bond donor5
XlogP6.2
SynonymsBDBM50284771
(S)-2-((R)-3-(2-Chloro-1H-indol-3-yl)-2-{2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-hexanoic acid
Inchi KeyGWMBPTBOMGCAGT-XXEUSHBOSA-N
Inchi IDInChI=1S/C31H46ClN5O5/c1-6-7-14-24(30(40)41)34-29(39)26(17-22-21-13-8-9-15-23(21)33-27(22)32)35-28(38)25(16-18(2)3)36-31(42)37-19(4)11-10-12-20(37)5/h8-9,13,15,18-20,24-26,33H,6-7,10-12,14,16-17H2,1-5H3,(H,34,39)(H,35,38)(H,36,42)(H,40,41)/t19-,20+,24-,25?,26+/m0/s1
PubChem CID44283349
ChEMBLCHEMBL289410
IUPHARN/A
BindingDB50284771
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
107044Endothelin receptor type BP35463EDNRBSus scrofa (Pig)443
107043Endothelin-1 receptorQ29010EDNRASus scrofa (Pig)427

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