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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL435218
Molecular formula	C23H25Cl2N3O2
IUPAC name	N-[4-[4-(2,4-dichlorophenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Molecular weight	446.372
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.5
Synonyms	Benzofuran-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide BDBM50131923
Inchi Key	GWZLKJUHKRQBRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25Cl2N3O2/c24-18-7-8-20(19(25)16-18)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29)
PubChem CID	10873978
ChEMBL	CHEMBL435218
IUPHAR	N/A
BindingDB	50131923
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
107393	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
107394	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
107391	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
107392	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
107395	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
107396	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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