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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3955752
Molecular formula	C22H18F2N4O2
IUPAC name	[(3S)-4,4-difluoro-3-quinolin-2-yloxypiperidin-1-yl]-imidazo[1,5-a]pyridin-8-ylmethanone
Molecular weight	408.409
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50203754
Inchi Key	HDXOKNFWVWBAOR-IBGZPJMESA-N
Inchi ID	InChI=1S/C22H18F2N4O2/c23-22(24)9-11-27(21(29)16-5-3-10-28-14-25-12-18(16)28)13-19(22)30-20-8-7-15-4-1-2-6-17(15)26-20/h1-8,10,12,14,19H,9,11,13H2/t19-/m0/s1
PubChem CID	134144954
ChEMBL	CHEMBL3955752
IUPHAR	N/A
BindingDB	50203754
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
549247	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
549250	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
549248	Orexin receptor type 2	P56719	Hcrtr2	Rattus norvegicus (Rat)	460
549249	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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