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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL142496
Molecular formula	C22H24FN3O4S
IUPAC name	8-[3-[4-(4-fluorobenzoyl)piperazin-1-yl]-2-hydroxypropoxy]-4H-1,4-benzothiazin-3-one
Molecular weight	445.509
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.8
Synonyms	BDBM50086675 8-[2-Hydroxy-3-[4-(4-fluorobenzoyl)piperazino]propoxy]-3,4-dihydro-2H-1,4-benzothiazine-3-one 8-{3-[4-(4-Fluoro-benzoyl)-piperazin-1-yl]-2-hydroxy-propoxy}-4H-benzo[1,4]thiazin-3-one
Inchi Key	HGLMWLKCPYICHB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24FN3O4S/c23-16-6-4-15(5-7-16)22(29)26-10-8-25(9-11-26)12-17(27)13-30-19-3-1-2-18-21(19)31-14-20(28)24-18/h1-7,17,27H,8-14H2,(H,24,28)
PubChem CID	44361774
ChEMBL	CHEMBL142496
IUPHAR	N/A
BindingDB	50086675
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
114197	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
114198	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415

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